Wang Y, Hashizume Y, Inagaki T
Institute for Medical Science of Aging, Aichi Medical University.
Nihon Ronen Igakkai Zasshi. 1996 Dec;33(12):935-9. doi: 10.3143/geriatrics.33.935.
To study vascular lesions of the spinal cord in the elderly, a pathological study of atheromatous emboli in the spinal cord was done. Among 604 patients examined at autopsy, atheromatous emboli of the spinal cord were found in 7 (1.2%). The average age of these patients was 76 years. The most common underlying disorders in these patients were hypertension, severe aortic atherosclerosis, and diabetes mellitus. Atheromatous emboli were also often found in the arteries of the kidneys, spleen, pancreas, and colon. The small arteries of the spinal arachnoid at the lumbosacral level were most frequently affected by the atheromatous emboli. Two patients had spinal-cord infarctions associated with atheromatous emboli: one had a cystic infarction of the lateral column at the T9 segment, and the other had cystic infarctions of the lateral column at the C7 and T3 segments. The low incidence of spinal cord infarction was attributed to good collateral circulation in the spinal cord. Atheromatous embolism should be considered as a possible cause of vascular lesions of the spinal cord in elderly persons with aortic atherosclerosis.
为研究老年人脊髓血管病变,对脊髓粥样硬化栓子进行了病理研究。在604例尸检患者中,发现7例(1.2%)存在脊髓粥样硬化栓子。这些患者的平均年龄为76岁。这些患者最常见的基础疾病是高血压、严重主动脉粥样硬化和糖尿病。在肾、脾、胰腺和结肠的动脉中也经常发现粥样硬化栓子。腰骶部脊髓蛛网膜的小动脉最常受粥样硬化栓子影响。两名患者发生了与粥样硬化栓子相关的脊髓梗死:1例在T9节段侧柱出现囊性梗死,另1例在C7和T3节段侧柱出现囊性梗死。脊髓梗死发生率低归因于脊髓良好的侧支循环。对于患有主动脉粥样硬化的老年人,应考虑粥样硬化栓塞是脊髓血管病变的可能原因。