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髓母细胞瘤放射治疗后发生颅内动脉瘤。一例病例报告并文献复习。

Intracranial aneurysm following radiation therapy for medulloblastoma. A case report and review of the literature.

作者信息

Jensen F K, Wagner A

机构信息

Department of Neuroradiology, Rigshospitalet, University of Copenhagen, Denmark.

出版信息

Acta Radiol. 1997 Jan;38(1):37-42. doi: 10.1080/02841859709171239.

Abstract

Radiation-induced intracranial aneurysm formation is a rare but life-threatening condition with a high mortality rate secondary to rupture of the aneurysm. Furthermore, this condition can mimic tumour recurrence. Only 10 months after craniospinal radiation therapy for medulloblastoma, a 9-year-old boy developed a subarachnoid haemorrhage secondary to a ruptured saccular aneurysm arising from the distal part of the right anterior cerebral artery. The development of intracranial aneurysms and rupture following radiation damage of the arteries has been reported previously, but in no case as soon as 10 months after radiation therapy. It is important to diagnose these aneurysms as they can be successfully treated.

摘要

放射性颅内动脉瘤形成是一种罕见但危及生命的疾病,动脉瘤破裂后死亡率很高。此外,这种情况可能会模仿肿瘤复发。一名9岁男孩在接受髓母细胞瘤的颅脊髓放射治疗仅10个月后,因右侧大脑前动脉远端出现的囊状动脉瘤破裂而发生蛛网膜下腔出血。此前已有关于动脉放射性损伤后颅内动脉瘤的发生和破裂的报道,但从未有在放射治疗后10个月这么短时间内发生的情况。诊断出这些动脉瘤很重要,因为它们可以得到成功治疗。

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