• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Hydroxysteroid dehydrogenases. New drug targets of the aldo-keto reductase superfamily.

作者信息

Penning T M

机构信息

Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia 19104-6084, USA.

出版信息

Adv Exp Med Biol. 1997;414:475-90.

PMID:9059653
Abstract
摘要

相似文献

1
Hydroxysteroid dehydrogenases. New drug targets of the aldo-keto reductase superfamily.羟类固醇脱氢酶。醛酮还原酶超家族的新药物靶点。
Adv Exp Med Biol. 1997;414:475-90.
2
Structure-function relationships in 3alpha-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms.3α-羟基类固醇脱氢酶的结构-功能关系:大鼠和人类同工型的比较
J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):247-55. doi: 10.1016/s0960-0760(03)00236-x.
3
Structure and function of 3 alpha-hydroxysteroid dehydrogenase.3α-羟基类固醇脱氢酶的结构与功能
Steroids. 1997 Jan;62(1):101-11. doi: 10.1016/s0039-128x(96)00167-5.
4
Mammalian 3 alpha-hydroxysteroid dehydrogenases.哺乳动物3α-羟基类固醇脱氢酶
Steroids. 1996 Sep;61(9):508-23. doi: 10.1016/s0039-128x(96)00093-1.
5
Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution.人类1型和3型3α-羟基类固醇脱氢酶:不同的稳定性和组织分布。
J Clin Endocrinol Metab. 2001 Feb;86(2):841-6. doi: 10.1210/jcem.86.2.7216.
6
Molecular cloning of human type 3 3 alpha-hydroxysteroid dehydrogenase that differs from 20 alpha-hydroxysteroid dehydrogenase by seven amino acids.人3型3α-羟基类固醇脱氢酶的分子克隆,其与20α-羟基类固醇脱氢酶在七个氨基酸上存在差异。
Biochem Biophys Res Commun. 1996 Nov 12;228(2):474-9. doi: 10.1006/bbrc.1996.1684.
7
Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily.大鼠肝脏3α-羟基类固醇/二氢二醇脱氢酶的三维结构:醛酮还原酶超家族的一员。
Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2517-21. doi: 10.1073/pnas.91.7.2517.
8
Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.人III型3α-羟基类固醇脱氢酶/胆汁酸结合蛋白与NADP(+)和熊去氧胆酸复合物的晶体结构
Biochemistry. 2001 Aug 28;40(34):10161-8. doi: 10.1021/bi010919a.
9
Cloning and expression of cDNA encoding hamster liver 3-hydroxyhexobarbital/17beta(3alpha)-hydroxysteroid dehydrogenase 1.仓鼠肝脏3-羟基己巴比妥/17β(3α)-羟基类固醇脱氢酶1编码cDNA的克隆与表达
Chem Biol Interact. 2001 Jan 30;130-132(1-3):863-70. doi: 10.1016/s0009-2797(00)00241-6.
10
Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.小鼠17α-羟基类固醇脱氢酶(AKR1C21)与其他醛酮还原酶结合类固醇的方式不同:对底物结合至关重要的氨基酸残基的鉴定与表征
J Mol Biol. 2007 Jun 1;369(2):525-40. doi: 10.1016/j.jmb.2007.03.058. Epub 2007 Mar 27.