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自然盲鼹形鼠(Spalax ehrenbergi)体感皮层及体感丘脑核的大小

Size of somatosensory cortex and of somatosensory thalamic nuclei of the naturally blind mole rat, Spalax ehrenbergi.

作者信息

Mann M D, Rehkämper G, Reinke H, Frahm H D, Necker R, Nevo E

机构信息

Department of Physiology and Biophysics, University of Nebraska, Omaha, USA.

出版信息

J Hirnforsch. 1997;38(1):47-59.

PMID:9059917
Abstract

The hypothesis that the somatosensory system in the naturally blind subterranean rodent Spalax ehrenbergi (= mole rat) is enlarged was tested by measuring the volume of somatosensory cortex and somatosensory thalamic nuclei (Nuclei ventrales posteromedialis and posterolateralis). Electrophysiology and tracing were used to identify and delineate these areas. On average the somatosensory cortex is 1.7 times larger and the thalamic nuclei are 1.3 times larger in the blind mole rat than in the sighted laboratory rat if different body weights are taken into consideration. This confirms the demands of a life underground where it seems touch would replace vision. The data reveal a remarkable brain plasticity among mammals under natural conditions.

摘要

通过测量体感皮层和体感丘脑核(腹后内侧核和腹后外侧核)的体积,对天生失明的地下啮齿动物斯氏鼹形鼠(Spalax ehrenbergi,即鼹鼠)的体感系统是否扩大这一假设进行了测试。利用电生理学和追踪技术来识别和描绘这些区域。如果考虑到不同的体重,平均而言,盲鼹鼠的体感皮层比有视力的实验大鼠大1.7倍,丘脑核大1.3倍。这证实了地下生活的需求,在这种环境下,触觉似乎会取代视觉。数据揭示了自然条件下哺乳动物中显著的大脑可塑性。

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1
Size of somatosensory cortex and of somatosensory thalamic nuclei of the naturally blind mole rat, Spalax ehrenbergi.自然盲鼹形鼠(Spalax ehrenbergi)体感皮层及体感丘脑核的大小
J Hirnforsch. 1997;38(1):47-59.
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Functional anatomy of the thalamus in the blind mole rat Spalax ehrenbergi: an architectonic and electrophysiologically controlled tracing study.
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Auditory pathway and auditory activation of primary visual targets in the blind mole rat (Spalax ehrenbergi): I. 2-deoxyglucose study of subcortical centers.盲鼹鼠(Spalax ehrenbergi)的听觉通路及初级视觉目标的听觉激活:I. 皮层下中枢的2-脱氧葡萄糖研究
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Elife. 2022 Jun 8;11:e78295. doi: 10.7554/eLife.78295.
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Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat.基因缺失可能有助于裸鼹鼠和盲鼹鼠的地下适应。
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Evolution under environmental stress at macro- and microscales.宏观和微观尺度下的环境胁迫下的进化。
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Circadian genes in a blind subterranean mammal II: conservation and uniqueness of the three Period homologs in the blind subterranean mole rat, Spalax ehrenbergi superspecies.一种盲鼹形地下哺乳动物的昼夜节律基因II:盲鼹形鼠Spalax ehrenbergi超种中三个Period同源基因的保守性与独特性
Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11718-23. doi: 10.1073/pnas.182423299. Epub 2002 Aug 22.
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Somatosensory cortex dominated by the representation of teeth in the naked mole-rat brain.裸鼹鼠大脑中由牙齿表征主导的躯体感觉皮层。
Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5692-7. doi: 10.1073/pnas.072097999. Epub 2002 Apr 9.