Vanek V W, Kupensky D T, Thomson D J
Department of Surgery, St. Elizabeth Health Center, Youngstown, Ohio, USA.
J Intraven Nurs. 1997 Jan-Feb;20(1):23-7.
Catheter-related hypersensitivity-type adverse reactions have been associated with insertion of the LANDMARK Midline Catheter (Menlo Care Inc., Menlo Park, CA). The authors' retrospective study showed an incidence for these reactions of 0.3% (7/2169) as well as an incidence of 3.3% (2/61) with insertion of CENTERMARK PICC (Menlo Care Inc., Menlo Park, CA), another aquavene-based catheter. The mechanism causing these reactions remains unknown, but the authors think that there is a small but significant risk of potentially life-threatening adverse reactions associated with insertion of these catheters. The health care professional who uses these catheters should be aware of these hypersensitivity reactions and should report any cases that occur to the Food and Drug Administration's MedWatch immediately.
与导管相关的超敏反应型不良反应与LANDMARK中线导管（Menlo Care公司，加利福尼亚州门洛帕克）的插入有关。作者的回顾性研究显示，这些反应的发生率为0.3%（7/2169），而插入另一种基于水凝胶的导管CENTERMARK PICC（Menlo Care公司，加利福尼亚州门洛帕克）时的发生率为3.3%（2/61）。引起这些反应的机制尚不清楚，但作者认为，插入这些导管会有小但显著的潜在危及生命的不良反应风险。使用这些导管的医护人员应了解这些超敏反应，并应立即向美国食品药品监督管理局的MedWatch报告发生的任何病例。
