Ghali R, Palazzo E G, Rodriguez D I, Zammit M, Loudenback D L, DeMuth R P, Spencer M P, Sauvage L R
Hope Heart Institute, Providence Medical Center, Seattle, WA 98122, USA.
Ann Vasc Surg. 1997 Jan;11(1):9-13. doi: 10.1007/s100169900003.
To determine whether continuous transcranial Doppler (TCD) can significantly alter therapeutic conduct during carotid endarterectomy, a retrospective study of 117 carotid endarterectomies was done. There was no perioperative mortality; one perioperative stroke was recorded in a patient who was symptomatic preoperatively. Continuous TCD of the ipsilateral middle cerebral artery (MCA) was attempted in 99 cases, and successful in 90; nine patients (9.1%) had inadequate temporal windows for MCA access. MCA velocities and emboli were recorded before and during carotid cross-clamping, and on clamp release. There were no significant velocity differences between the patients with regional and general anesthesia, and patients with and without carotid shunts, but there was a statistically significant difference in the total number of emboli (air and particulate transients) noted for the shunted and nonshunted patients after clamp release: 12.7 versus 23.6, respectively (p = 0.05). There was no significant difference when particulate and air microemboli were compared. During surgery TCD identified residual flow of less than 40% in the MCA in 17 patients (18.8%). TCD also identified hyperperfusion in two patients, shunt abnormalities in three patients, and influenced postop treatment in four patients, one of whom was returned to surgery. TCD is an important tool for identifying patients who would benefit from a shunt, preventing hyperperfusion, identifying postop emboli, and detecting technical errors.
为了确定连续经颅多普勒(TCD)是否能在颈动脉内膜切除术期间显著改变治疗行为,对117例颈动脉内膜切除术进行了回顾性研究。围手术期无死亡病例;术前有症状的1例患者发生围手术期卒中。99例患者尝试对同侧大脑中动脉(MCA)进行连续TCD监测,90例成功;9例患者(9.1%)因颞窗不佳无法进行MCA监测。记录颈动脉夹闭前、夹闭期间及松开夹闭时的MCA血流速度和栓子情况。区域麻醉与全身麻醉患者之间、使用与未使用颈动脉分流管的患者之间,血流速度无显著差异,但松开夹闭后,使用与未使用分流管的患者记录到的栓子总数(空气和颗粒性短暂信号)有统计学显著差异:分别为12.7和23.6(p = 0.05)。比较颗粒性和空气微栓子时无显著差异。手术期间,TCD发现17例患者(18.8%)的MCA残余血流小于40%。TCD还发现2例患者存在高灌注,3例患者存在分流异常,并影响了4例患者的术后治疗,其中1例返回手术室再次手术。TCD是一种重要工具,可用于识别能从分流管中获益的患者、预防高灌注、识别术后栓子及检测技术失误。