Ide J, Yamaga M, Kitamura T, Takagi K
Department of Orthopaedic Surgery, Kumamoto University School of Medicine, Japan.
J Hand Surg Br. 1997 Feb;22(1):102-6. doi: 10.1016/s0266-7681(97)80031-9.
The sympathetic nervous system function in 20 patients with reflex sympathetic dystrophy (RSD) of one upper extremity was examined by a non-invasive laser Doppler method to assess fingertip blood flow and vasoconstrictor response to deep inspiration. We observed an increased blood flow but an unchanged vasoconstrictor response in the affected hand in stage 1 of the disorder, but in stage 2 there was a decreased blood flow and a stronger vasoconstriction following an inspiratory gasp. Skin blood flow and vasoconstrictor response returned to normal following successful treatment of the condition. These results suggest that in RSD patients the sympathetic nervous system function is altered and is different in the various stages. The objective method used in our study may be of value in the diagnosis and management of RSD.
采用非侵入性激光多普勒方法，对20例单侧上肢反射性交感神经营养不良（RSD）患者的交感神经系统功能进行检测，以评估指尖血流量及深吸气时血管收缩反应。我们观察到，在疾病第1阶段，患手血流量增加，但血管收缩反应未改变；而在第2阶段，吸气后血流量减少，血管收缩增强。病情成功治疗后，皮肤血流量和血管收缩反应恢复正常。这些结果表明，RSD患者的交感神经系统功能发生改变，且在不同阶段有所不同。我们研究中使用的客观方法可能对RSD的诊断和治疗具有价值。
