Bauer J, Helmstaedter C, Elger C E
Department of Epileptology, University of Bonn, Germany.
Seizure. 1997 Feb;6(1):67-70. doi: 10.1016/s1059-1311(97)80056-8.
We report the case of a 55-year-old patient with infrequent generalized tonic-clonic seizures since the age of 40 years and additional frequent episodes of disturbed behaviour and impaired cognition. The latter last from several hours up to one day with sudden onset and end of electroencephalographic (EEG) changes and clinical manifestations. They occurred about once a week before they were successfully treated with valproate and lamotrigine. From clinical, therapeutic and EEG findings we conclude that the patient suffers from nonconvulsive status epileptici, although the ictal EEG showed an untypical pattern of monomorphic generalized alpha rhythm. Many EEG characteristics point towards a primary generalized seizure disorder but a focal origin with secondary bilateral synchrony has to be considered as well. However, this is obviously a rare type which has not been described previously.
我们报告了一例55岁患者的病例,该患者自40岁起偶发全身性强直阵挛性癫痫,此外还频繁出现行为障碍和认知受损发作。后者持续数小时至一天,脑电图(EEG)变化和临床表现突然发作和结束。在使用丙戊酸盐和拉莫三嗪成功治疗之前,它们大约每周发生一次。从临床、治疗和脑电图检查结果来看,我们得出结论,该患者患有非惊厥性癫痫持续状态,尽管发作期脑电图显示出非典型的单形性全身性α节律模式。许多脑电图特征指向原发性全身性癫痫发作障碍,但也必须考虑局灶性起源伴继发性双侧同步。然而,这显然是一种罕见的类型,此前尚未有过描述。