Savov N, Buchvarova Ia
Vet Med Nauki. 1977;14(3):3-8.
A total of 313 cows were investigated in order to establish the agents that most frequently caused genital diseases in cows on 5 farms where the experiments were carried out. In animals that had miscarried as well as in those that had recovered from metritis specific antibodies were found against the isolated causative agents, having titers in the vaginal mucus from 1:160 to 1:320, and in the blood serum--from 1:160 up to 1:1280. Strains were selected from the most frequently isolated bacterial species to produce a killed polybacterial adsorbate baccine. It was used 152 cows on the same farms in the eighth month of first or second gestation. The treated animals built immunity of a varying intensity, which was demonstrated with the appearance of specific antibodies of titers in the vaginal mucus ranging from 1:80 to 1:640, and in the blood serum--from 1:80 to 1:1280, and with marked resistance against the bacterial agents used in the vaccine.
为了确定在进行实验的5个农场中最常导致奶牛生殖疾病的病原体,共对313头奶牛进行了调查。在流产的动物以及从子宫炎中恢复的动物体内,发现了针对分离出的病原体的特异性抗体,其在阴道黏液中的滴度为1:160至1:320,在血清中的滴度为1:160至1:1280。从最常分离出的细菌种类中挑选菌株,制备了一种灭活多菌吸附疫苗。在同一农场的152头处于首次或第二次妊娠第八个月的奶牛身上使用了该疫苗。接受治疗的动物产生了强度各异的免疫力,这表现为阴道黏液中特异性抗体滴度达到1:80至1:640,血清中达到1:80至1:1280,并且对疫苗中使用的细菌病原体具有显著抗性。