Hung O L, Shih R D, Chiang W K, Nelson L S, Hoffman R S, Goldfrank L R
Department of Emergency Medicine, New York University Medical Center, Bellevue Hospital Center, New York, USA.
Acad Emerg Med. 1997 Mar;4(3):209-13. doi: 10.1111/j.1553-2712.1997.tb03743.x.
To determine the prevalence of herbal preparation use among patients presenting to an urban teaching hospital ED.
A prospective anonymous survey on herbal preparation use was performed. Consecutive, acutely ill or injured adult (> or = 18 years old) ED patients were offered the survey over a 1-month period. The survey also asked for information related to patient age, ethnicity, gender, employment, education, cigarette smoking history, ethanol consumption, use of illicit drugs, chief complaint, and HIV status.
Of 2,473 eligible subjects, 623 (25%) participated. The overall reported prevalence of herbal preparation use among the participants was 21.7%. Women were more likely to use herbal preparations than men (28.5% vs 17.2%, p = 0.013). Prevalence rates in different ethnic populations were: whites, 18.2%; Hispanics, 13.9%; blacks, 26.4%; and Asians, 36.8%. Asians had a significantly higher use rate than the other ethnic groups (p = 0.039). Neither HIV positivity, educational level, employment status, nor age was significantly associated with herbal preparation use. The most commonly reported herbal preparations were goldenseal tea, garlic, and ginger. Several of the herbal preparations reported as used by patients in this study have been associated with severe systemic toxicity in the medical literature.
Although the survey response rate was low, the prevalence of herbal preparation use among acutely ill or injured patients presenting to this urban ED remains significant. A directed history toward specific herbal preparation use may provide relevant pharmacologic information and uncover cases of herbal-preparation-induced toxicity.
确定前往城市教学医院急诊科就诊的患者中使用草药制剂的比例。
对草药制剂的使用情况进行了一项前瞻性匿名调查。在1个月的时间里,连续向急性病或受伤的成年(≥18岁)急诊科患者提供该调查。该调查还询问了有关患者年龄、种族、性别、职业、教育程度、吸烟史、饮酒情况、非法药物使用情况、主要症状以及艾滋病毒感染状况的信息。
在2473名符合条件的受试者中,623人(25%)参与了调查。参与者中报告使用草药制剂的总体比例为21.7%。女性比男性更有可能使用草药制剂(28.5%对17.2%,p = 0.013)。不同种族人群的使用率分别为:白人,18.2%;西班牙裔,13.9%;黑人,26.4%;亚洲人,36.8%。亚洲人的使用率明显高于其他种族群体(p = 0.039)。艾滋病毒阳性、教育程度、就业状况和年龄均与草药制剂的使用无显著关联。最常报告使用的草药制剂是白毛茛茶、大蒜和生姜。本研究中患者报告使用的几种草药制剂在医学文献中已被证明与严重的全身毒性有关。
尽管调查回复率较低,但在这家城市急诊科就诊的急性病或受伤患者中,草药制剂的使用率仍然很高。针对特定草药制剂使用情况的定向问诊可能会提供相关的药理学信息,并发现草药制剂引起的中毒病例。