Sudenko V I, Groma L I, Podgorskiĭ V S
Mikrobiol Z. 1996 Nov-Dec;58(6):38-44.
Differences in species composition, number and level of antagonistic activity of bacteria isolated from the digestive tract of Chernobyl female minks of various age and with different immunological state have been established. Prevalence of anaerobes (bifidobacteria) and microaerophils (lactic acid bacteria) with the increase of microorganisms concentration along the channel: stomach, small and large intestine (10(7)-10(10)/g) was found in all the departments of digestive tract of minks. Among the identified lactic-acid bacteria Lactobacillus helveticus (10(7)-10(8)/g) prevailed in the stomach of the studied female minks, L. coryniformis (10(9)-10(10)/g) in the small intestine, L. casei (10(10)/g) in the large one. Antagonistic activity was most expressed in the strains of L. helveticus and L. casei, isolated from the younger (1.5 year-old) minks. Enterococcus faecalis isolated from the stomach of 1.5 year-old female minks was distinguished by the greatest antagonistic activity among identified enterococci. Strains of E. faecium isolated from the thin intestine of the young female minks (1.5 year-old) and from the large intestine of more nature animals (2.5 years) who received thymogen were characterized by the most expressed antibiosis among enterococci isolated bacteria a conclusion was made that the mechanisms of inhibitory effect of the studied microorganisms are underlied by not only their capacity to form organic acids but also by the capacity to produce antibiotic products.
已确定从不同年龄和免疫状态的切尔诺贝利雌性水貂消化道分离出的细菌在物种组成、数量和拮抗活性水平上存在差异。在水貂消化道的所有部位都发现，随着沿消化道通道（胃、小肠和大肠）微生物浓度的增加（10⁷ - 10¹⁰/g），厌氧菌（双歧杆菌）和微需氧菌（乳酸菌）占优势。在所鉴定的乳酸菌中，瑞士乳杆菌（10⁷ - 10⁸/g）在被研究雌性水貂的胃中占主导，棒状乳杆菌（10⁹ - 10¹⁰/g）在小肠中占主导，干酪乳杆菌（10¹⁰/g）在大肠中占主导。拮抗活性在从较年轻（1.5岁）水貂分离出的瑞士乳杆菌和干酪乳杆菌菌株中表现最为明显。从1.5岁雌性水貂胃中分离出的粪肠球菌在已鉴定的肠球菌中具有最大的拮抗活性。从年轻雌性水貂（1.5岁）小肠和接受胸腺素的更年长动物（2.5岁）大肠中分离出的屎肠球菌菌株在分离出的肠球菌中具有最明显的抗菌作用。得出的结论是，所研究微生物的抑制作用机制不仅在于它们形成有机酸的能力，还在于产生抗生素产物的能力。
