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[幻觉状态的发病机制综述。四例病例描述]

[A review of the pathogenesis of the hallucinatory state. A description of four case].

作者信息

Tapiador M J, López-López A, Ayuso T

机构信息

Unidad de Neurología Ambulatoria, Teruel, Hospital Obispo Polanco, España.

出版信息

Rev Neurol. 1996 Dec;24(136):1529-32.

PMID:9064168
Abstract

INTRODUCTION

A hallucination is a sensorial experience occurring in the absence of external stimuli. It may show as psychological or organic disorders. The main causes are lesions of the central nervous system and of the sensorial organs. The hallucination may present with or without critical perception but always appears to be a real experience.

CLINICAL CASE

We describe four patients diagnosed as having hallucinations secondary to known lesions. The first two had visual hallucinations and cerebral ischaemia, the first in the dorso-lateral region of the medulla oblongata and the second in the left parietal lobe. The other two had peripheral sensorial defects. The third patient had simultaneously an ophthalmic disorder and visual hallucinations, and the fourth had chronic hypoacusia and auditory hallucinations. All showed structured sensorial hallucinations with critical appraisal of these hallucinations.

CONCLUSIONS

In this paper we review the pathogenesis of the organic hallucinatory state. The main mechanisms are proposed: by means of liberation (destruction of inhibitory structures) and by means of irritation (anomolous excitation of cerebral structures). Also we point out the difference between a hallucination and psychiatric disorders, mainly in three aspects: presence of the known organic lesion, critical appraisal of the perception in spite of it appearing as real to the patient, and the absence of associated psychiatric pathology.

摘要

引言

幻觉是在没有外部刺激的情况下发生的一种感觉体验。它可能表现为心理或器质性障碍。主要病因是中枢神经系统和感觉器官的病变。幻觉可能伴有或不伴有批判性感知,但总是表现为一种真实的体验。

临床病例

我们描述了四名被诊断为继发于已知病变的幻觉患者。前两名患者有视觉幻觉和脑缺血,第一名患者病变位于延髓背外侧区,第二名患者病变位于左侧顶叶。另外两名患者有周围感觉缺陷。第三名患者同时患有眼部疾病和视觉幻觉,第四名患者患有慢性听力减退和听觉幻觉。所有患者均表现为有组织的感觉性幻觉,并对这些幻觉进行了批判性评估。

结论

在本文中,我们回顾了器质性幻觉状态的发病机制。提出了主要机制:通过释放(抑制结构的破坏)和通过刺激(脑结构的异常兴奋)。我们还指出了幻觉与精神疾病之间的区别,主要在三个方面:存在已知的器质性病变、尽管对患者来说幻觉看起来真实但仍对感知进行批判性评估、以及不存在相关的精神病理学。

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