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[镁:当前研究——批判性评估——影响]

[Magnesium: current studies--critical evaluation--consequences].

作者信息

Meinertz T

机构信息

Abteilung für Kardiologie, Universitätskrankenhaus Eppendorf, Hamburg.

出版信息

Z Kardiol. 1996;85 Suppl 6:147-51.

PMID:9064959
Abstract

The therapeutic efficacy of magnesium has been studied during recent years in a number of cardiovascular diseases: supraventricular and ventricular arrhythmias (multifocal atrial tachycardia, Torsade de pointes-tachycardia, glycoside-associated arrhythmias, sustained ventricular tachycardia), acute myocardial infarction, heart failure and arterial hypertension. Although only a few of these arrhythmias were studied under controlled conditions, the therapeutic efficacy of intravenous magnesium given in a high dose in these arrhythmias seems to be established. By contrary, the efficacy of magnesium in acute myocardial infarction, congestive heart failure and arterial hypertension remains controversial up to now. Magnesium cannot be regarded as standard therapy for example for patients with acute myocardial infarction.

摘要

近年来,镁的治疗效果已在多种心血管疾病中得到研究:室上性和室性心律失常(多源性房性心动过速、尖端扭转型室性心动过速、洋地黄相关性心律失常、持续性室性心动过速)、急性心肌梗死、心力衰竭和动脉高血压。尽管这些心律失常中只有少数是在对照条件下进行研究的,但高剂量静脉注射镁在这些心律失常中的治疗效果似乎已经得到证实。相反,镁在急性心肌梗死、充血性心力衰竭和动脉高血压中的疗效至今仍存在争议。例如,镁不能被视为急性心肌梗死患者的标准治疗方法。

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