Finelli L, Nakashima A K, Hillis S, Crayne E, Spitalny K C
Sexually Transmitted Diseases Prevention and Control Program, New Jersey Department of Health, Trenton 08625-0369, USA.
Am J Obstet Gynecol. 1996 May;174(5):1527-33. doi: 10.1016/s0002-9378(96)70601-4.
Our goals were to determine the prevalence of chlamydial infection, to identify criteria for selective screening, and to compare the sensitivity of selective screening to presumptive treatment criteria in different clinical settings.
A total of 5128 women enrolled in a cross-sectional study in public clinics in New Jersey. Univariate and multivariate methods of statistical analysis were used.
The prevalence of chlamydia varied across type of public clinic and ranged from 8% to 15%. Selective screening criteria were developed for women attending each type of public clinic by use of risk factors significant in the multivariate analyses. A combination of young age and attending an urban clinic was highly predictive of chlamydia infection and identified a minimum of 85% of infected women in all public clinic settings. The use of presumptive treatment criteria identified 78% of infected women in sexually transmitted disease clinics but only 4% to 9% of infected women in other clinical settings.
A chlamydia program that includes presumptive treatment of women attending sexually transmitted disease clinics and selective screening of women in other clinical settings where women are more likely to asymptomatic is a clinically appropriate and economically feasible approach to directing treatment of women with chlamydial infection.
我们的目标是确定衣原体感染的患病率，确定选择性筛查的标准，并比较在不同临床环境中选择性筛查与推定治疗标准的敏感性。
共有5128名女性参与了新泽西州公共诊所的一项横断面研究。使用了单变量和多变量统计分析方法。
衣原体的患病率因公共诊所类型而异，范围在8%至15%之间。通过使用多变量分析中有显著意义的危险因素，为每种类型公共诊所的就诊女性制定了选择性筛查标准。年轻且在城市诊所就诊这一组合对衣原体感染具有高度预测性，在所有公共诊所环境中能识别出至少85%的感染女性。使用推定治疗标准在性传播疾病诊所中识别出78%的感染女性，但在其他临床环境中仅识别出4%至9%的感染女性。
一个衣原体项目，包括对性传播疾病诊所的就诊女性进行推定治疗，以及对其他女性更可能无症状的临床环境中的女性进行选择性筛查，是指导衣原体感染女性治疗的一种临床适宜且经济可行的方法。
