Leone O, Piana S, Cenacchi G, Farneti P A, Pilato E, Pacini D, Galli R, Santini D, Pileri S
Institute of Pathology, University of Bologna, Italy.
Gen Diagn Pathol. 1997 Feb;142(3-4):235-40.
We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.
我们报告一例45岁女性肺静脉肿瘤病例，该患者表现为进行性呼吸困难。结果，肿瘤充满整个左心房，手术切除时似乎附着于左上肺静脉。组织学上，它由肉瘤样细胞增殖组成，有高有丝分裂率，平滑肌肌动蛋白免疫组化弥漫阳性，符合平滑肌肉瘤。讨论了显微镜、免疫组化和超微结构的发现。
