Katunguka-Rwakishaya E
University of Glasgow Veterinary School, UK.
Vet Parasitol. 1997 Feb;68(3):227-40. doi: 10.1016/s0304-4017(96)01057-6.
The present study investigated the influence of dietary protein on some blood biochemical parameters, namely lipids, proteins, iron, glucose and B-hydroxybutyrate, in Scottish Blackface sheep infected with Trypanosoma congolense, and given either a low protein (51.5 g digestible crude protein per day) or a high protein (116 g digestible crude protein per day) diet. Both low and high protein diets were isocaloric and animals were monitored for 10 weeks after infection. It was observed that infection was associated with marked reduction in the concentrations of plasma total lipids, cholesterol, phospholipids and non-esterified fatty acids in both dietary groups. Control animals on a high protein diet had higher concentrations of plasma total lipids and cholesterol than those on a low protein diet. Infection caused severe hypoalbuminaemia and reduction in total iron-binding capacity only in the low protein infected group compared to their controls while the changes in the high protein infected and control groups were similar. Control animals receiving a high protein diet had higher concentrations of plasma albumin and total iron-binding capacity than those receiving a low protein diet. These observations suggest that Trypanosoma congolense infection in sheep is associated with marked changes in blood biochemical parameters, some of which are influenced by dietary protein.
本研究调查了日粮蛋白质对感染刚果锥虫的苏格兰黑脸羊某些血液生化参数的影响，这些参数包括脂质、蛋白质、铁、葡萄糖和β-羟基丁酸，试验羊分别给予低蛋白（每天51.5克可消化粗蛋白）或高蛋白（每天116克可消化粗蛋白）日粮。低蛋白和高蛋白日粮的热量相等，感染后对动物进行了10周的监测。结果发现，两个日粮组的感染均与血浆总脂质、胆固醇、磷脂和非酯化脂肪酸浓度的显著降低有关。高蛋白日粮的对照动物血浆总脂质和胆固醇浓度高于低蛋白日粮的对照动物。与各自的对照组相比，感染仅在低蛋白感染组导致严重的低白蛋白血症和总铁结合能力降低，而高蛋白感染组和对照组的变化相似。接受高蛋白日粮的对照动物血浆白蛋白和总铁结合能力浓度高于接受低蛋白日粮的对照动物。这些观察结果表明，绵羊感染刚果锥虫与血液生化参数的显著变化有关，其中一些变化受日粮蛋白质的影响。
