Jukkala-Partio K, Laitinen O, Partio E K, Vasenius J, Vainionpää S, Pohjonen T, Törmälä P, Rokkanen P
Department of Orthopaedics and Traumatology, University Central Hospital, Helsinki, Finland.
J Orthop Res. 1997 Jan;15(1):124-7. doi: 10.1002/jor.1100150118.
Seven subcapital femoral osteotomies of adult sheep were each fixed with two absorbable self-reinforced poly-L-lactide lag-screws, and seven other osteotomies were each fixed with two metallic cancellous bone screws. At 3 and 12 weeks, radiographs were taken and callus formation, displacement, and union were evaluated. At 12 weeks, the animals were killed and strength measurements were carried out. According to the radiographs, union was achieved in six of seven osteotomies in both groups, while after 3 weeks one fixation in both the group treated with absorbable screws and the group treated with metallic screws had failed. There were no statistical differences between the groups with respect to callus formation or displacement. Regarding the strength of the osteotomized bones, at 12 weeks there were no statistically significant differences in the load-carrying capacity between the bones fixed with self-reinforced poly-L-lactide screws and those fixed with metallic screws. These results showed that self-reinforced poly-L-lactide screws, which have been used successfully in fractures and osteotomies in cancellous bone, are strong enough to support this more demanding fixation of weight-bearing bones.
对成年绵羊的七处股骨颈下截骨术分别用两枚可吸收自增强聚-L-丙交酯拉力螺钉进行固定，另外七处截骨术则分别用两枚金属松质骨螺钉进行固定。在3周和12周时拍摄X线片，评估骨痂形成、移位及愈合情况。在12周时，处死动物并进行强度测量。根据X线片，两组中七处截骨术均有六处实现了愈合，而在3周后，可吸收螺钉治疗组和金属螺钉治疗组均有一处固定失败。两组在骨痂形成或移位方面无统计学差异。关于截骨骨的强度，在12周时，用自增强聚-L-丙交酯螺钉固定的骨与用金属螺钉固定的骨在承载能力方面无统计学显著差异。这些结果表明，已成功用于松质骨骨折和截骨术的自增强聚-L-丙交酯螺钉，足以牢固地固定这种对承重骨要求更高的固定。
