Look P, Kleinau W, Henze E
Zentralbl Chir. 1977;102(16):998-1005.
224 cases of fistula carcinoma arising from chronic osteomyelitis from literature and 6 own observations are reviewed. This malignancy results in about 1,5% cases of chronic osteomyelitis. The mean age of all patients was 55.7 years. The sex relation male to female was 7.4:1. The time from the beginning of the chronic osteomyelitis up to the diagnosis of the fistula carcinoma was 33.6 years. This time is called "Exposition time". The analysis of this time shows that, the older the patient was at the beginning of the chronic osteomyelitis the shorter was the exposition time.
回顾了文献中224例慢性骨髓炎引起的瘘管癌病例以及6例本人观察的病例。这种恶性肿瘤约占慢性骨髓炎病例的1.5%。所有患者的平均年龄为55.7岁。男女比例为7.4:1。从慢性骨髓炎开始到瘘管癌诊断的时间为33.6年。这段时间称为“暴露时间”。对这段时间的分析表明，慢性骨髓炎开始时患者年龄越大，暴露时间越短。
