Suga K, Nishigauchi K, Shimizu K, Kume N, Matsunaga N, Sato Y, Tangoku A, Kouichi N, Esato K
Department of Radiology, Yamaguchi University School of Medicine, Japan.
Clin Nucl Med. 1997 Mar;22(3):141-6. doi: 10.1097/00003072-199703000-00001.
In two patients with relapsed thrombocytopenia, the authors used SPECT with In-111 labeled autologous platelets to identify residual splenic tissue after splenectomy. One case involved a previously splenectomized patient with idiopathic portal hypertension, while the other had relapsed chronic idiopathic thrombocytopenic purpura (ITP). In both patients, SPECT showed a higher In-111 uptake in the splenic tissues compared with planar images. In the patient with ITP, a small accessory spleen had been overlooked on abdominal CT because of post-operative changes, but it was identified by superimposition of SPECT/CT images. These cases indicate that In-111 platelet SPECT is useful in detecting and localizing residual accessory splenic tissue associated with relapsed thrombocytopenia.
在两名血小板减少症复发的患者中，作者使用铟-111标记的自体血小板进行单光子发射计算机断层扫描（SPECT），以识别脾切除术后残留的脾组织。其中一例涉及一名既往接受过脾切除术的特发性门静脉高压患者，另一例为慢性特发性血小板减少性紫癜（ITP）复发患者。在这两名患者中，与平面图像相比，SPECT显示脾组织对铟-111的摄取更高。在ITP患者中，由于术后改变，腹部CT漏诊了一个小的副脾，但通过SPECT/CT图像叠加得以识别。这些病例表明，铟-111血小板SPECT有助于检测和定位与血小板减少症复发相关的残留副脾组织。
