Tsuchiya A, Abe R, Kanno M, Ohtake T, Fukushima T, Nomizu T, Kimijima I
Second Department of Surgery, Fukushima Medical College, Japan.
Surg Today. 1997;27(3):213-6. doi: 10.1007/BF00941647.
The effect of age on the prognosis of breast cancer remains controversial. To investigate the role of age, we reviewed 316 patients with stage I or II breast cancer. There were 14 patients below 34, 146 between 35 and 49, 115 between 50 and 65, and 41 over 66 years of age. No correlations were observed between age and clinicopathological variables. Breast cancer patients aged 34 or less had a significantly worse survival compared to those in the older age groups. Multivariate analysis also showed younger age to be a significant factor, followed by lymph node status. Therefore, younger age at onset is considered to be an independent prognostic factor.
年龄对乳腺癌预后的影响仍存在争议。为研究年龄的作用，我们回顾了316例I期或II期乳腺癌患者。年龄在34岁以下的有14例，35至49岁的有146例，50至65岁的有115例，66岁以上的有41例。未观察到年龄与临床病理变量之间存在相关性。与年龄较大的组相比，34岁及以下的乳腺癌患者生存率明显更差。多因素分析还显示，年龄较小是一个显著因素，其次是淋巴结状态。因此，发病时年龄较小被认为是一个独立的预后因素。
