Lobrano M B, McCarthy K, Adams L, Neitzschman H
Department of Radiology, Louisiana State University Medical Center, New Orleans, USA.
Am J Gastroenterol. 1997 Mar;92(3):513-5.
Radiolabeled somatostatin analogs have shown uptake in a variety of tumors. These include carcinoid, Merkel cell carcinoma, pheochromocytoma, islet cell tumor, and other tumors with somatostatin receptors. Radiolabeled somatostatin analog imaging with Indium-111-DTPA-pentetreotide permits whole body imaging, providing a new safe and effective means for detection of primary tumors and metastatic foci in neoplasms with somatostatin receptors. This imaging modality is helpful in screening the entire body as well as evaluating questionable foci of disease identified by conventional imaging modalities. This case report demonstrates the utility of computed tomography (CT) and radiolabeled somatostatin imaging as complementary modalities in the workup of a patient with metastatic carcinoid tumor.
放射性标记的生长抑素类似物已显示在多种肿瘤中摄取。这些肿瘤包括类癌、默克尔细胞癌、嗜铬细胞瘤、胰岛细胞瘤以及其他具有生长抑素受体的肿瘤。用铟 - 111 - DTPA - 喷替肽进行放射性标记的生长抑素类似物成像可进行全身成像,为检测具有生长抑素受体的肿瘤中的原发性肿瘤和转移灶提供了一种新的安全有效的方法。这种成像方式有助于对全身进行筛查,以及评估通过传统成像方式发现的可疑病灶。本病例报告展示了计算机断层扫描(CT)和放射性标记的生长抑素成像作为互补方式在转移性类癌肿瘤患者检查中的应用。