疱疹样皮炎与大疱性类天疱疮：免疫电镜证实的一种正在形成的关联
Dermatitis herpetiformis and bullous pemphigoid: a developing association confirmed by immunoelectronmicroscopy.
作者信息
Setterfield J, Bhogal B, Black M M, McGibbon D H
机构信息
St John's Institute of Dermatology (UMDS), St Thomas' Hospital, London, U.K.
出版信息
Br J Dermatol. 1997 Feb;136(2):253-6.
We report a case of dermatitis herpetiformis associated with bullous pemphigoid in which the clinical, histopathological and immunopathological findings were corroborated by direct immunoelectronmicroscopy performed on normal and peri-lesional skin biopsies. Western immunoblotting detected the 180 kDa BPAG2 consistent with bullous pemphigoid. HLA-typing confirmed the DR3 DQ2 haplotype associated with dermatitis herpetiformis.
我们报告1例疱疹样皮炎合并大疱性类天疱疮的病例，其中临床、组织病理学和免疫病理学检查结果通过对正常皮肤和皮损周围皮肤活检标本进行直接免疫电镜检查得以证实。蛋白质免疫印迹法检测到与大疱性类天疱疮相符的180 kDa大疱性类天疱疮抗原2（BPAG2）。人类白细胞抗原（HLA）分型证实了与疱疹样皮炎相关的DR3 DQ2单倍型。
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