Pimozide (Orap) in patients with pseudo-neurotic behaviour.

Pimozide 2-12 mg (median 4 mg) was tried for ten weeks in 44 pseudo-neurotic patients. Unsuccessfully used tranquillizers were continued and the use of the antiparkinsonian agent dexetimide was allowed if needed. By the end of the study, a considerable improvement was observed for the vast majority of the items of the Wittenborn psychiatric scale. Their socio-professional adaptation showed a similar tendency. Dexetimide was required in four patients who received high doses of pimozide.