普伐他汀与环孢素在移植患者中的联合应用。 - Suppr

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超能文献

Combination of pravastatin and cyclosporin in transplant patients.

作者信息

Christians U

出版信息

Clin Pharmacokinet. 1997 Feb;32(2):173-4. doi: 10.2165/00003088-199732020-00006.

DOI:10.2165/00003088-199732020-00006

PMID:9068930

Abstract

摘要

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Combination of pravastatin and cyclosporin in transplant patients.普伐他汀与环孢素在移植患者中的联合应用。

Clin Pharmacokinet. 1997 Feb;32(2):173-4. doi: 10.2165/00003088-199732020-00006.

Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A.服用环孢素A的心脏移植患者中普伐他汀的药代动力学

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Comparison of pravastatin and lovastatin in renal transplant patients receiving cyclosporine.普伐他汀与洛伐他汀在接受环孢素治疗的肾移植患者中的比较。

Transplant Proc. 1996 Dec;28(6):3126-8.

The inhibitory effects of pravastatin on natural killer cell activity in vivo and on cytotoxic T lymphocyte activity in vitro.普伐他汀对体内自然杀伤细胞活性及体外细胞毒性T淋巴细胞活性的抑制作用。

J Heart Lung Transplant. 1998 Apr;17(4):335-40.

Effects of simvastatin and pravastatin on hyperlipidemia and cyclosporin blood levels in renal transplant recipients.辛伐他汀和普伐他汀对肾移植受者高脂血症及环孢素血药浓度的影响。

Am J Nephrol. 1999;19(3):411-5. doi: 10.1159/000013487.

Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses.多次给药后，环孢素治疗的肾移植患者血液中洛伐他汀（而非普伐他汀）的蓄积情况。

Clin Pharmacol Ther. 1997 Sep;62(3):311-21. doi: 10.1016/S0009-9236(97)90034-5.

Drugs in cardiac transplantation.心脏移植中的药物

N Engl J Med. 1996 Feb 8;334(6):400-1; author reply 401-2.

Pharmacokinetics and pharmacodynamics of fluvastatin in heart transplant recipients taking cyclosporine A.氟伐他汀在接受环孢素A治疗的心脏移植受者中的药代动力学和药效学。

J Cardiovasc Pharmacol Ther. 2001 Oct;6(4):351-61. doi: 10.1177/107424840100600404.

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Rev Clin Esp. 2002 Sep;202(9):489-91. doi: 10.1016/s0014-2565(02)71120-x.

Effects of pravastatin in heart transplant recipients: implications of Kobashigawa et al.普伐他汀对心脏移植受者的影响：小川等人的研究启示

Curr Opin Lipidol. 1995 Dec;6(6):341-3. doi: 10.1097/00041433-199512000-00001.

引用本文的文献

Does differing metabolism by cytochrome p450 have clinical importance?细胞色素P450的代谢差异具有临床重要性吗？

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Drug interactions of lipid-altering drugs.

Drug Saf. 1998 Nov;19(5):355-71. doi: 10.2165/00002018-199819050-00003.

本文引用的文献

Clinically significant drug interactions with cyclosporin. An update.环孢素的具有临床意义的药物相互作用。最新进展。

Clin Pharmacokinet. 1996 Feb;30(2):141-79. doi: 10.2165/00003088-199630020-00004.

In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors.HMG-CoA还原酶抑制剂对主要人体药物代谢细胞色素P450同工酶（CYP2C9、CYP2D6和CYP3A4）的体外比较抑制谱

Eur J Clin Pharmacol. 1996;50(3):209-15. doi: 10.1007/s002280050094.

Dual roles of HMG-CoA reductase inhibitors in solid organ transplantation: lipid lowering and immunosuppression.

Kidney Int Suppl. 1995 Dec;52:S112-5.

Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia.HMG-CoA还原酶抑制剂单药治疗原发性高胆固醇血症的安全性和有效性的比较评估。

Ann Pharmacother. 1995 Jul-Aug;29(7-8):743-59. doi: 10.1177/106002809502907-818.

Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients.

Transplant Proc. 1993 Aug;25(4):2732-4.

Low-dose simvastatin is a well-tolerated and efficacious cholesterol-lowering agent in ciclosporin-treated kidney transplant recipients: double-blind, randomized, placebo-controlled study in 40 patients.低剂量辛伐他汀对于接受环孢素治疗的肾移植受者而言，是一种耐受性良好且有效的降胆固醇药物：一项针对40例患者的双盲、随机、安慰剂对照研究。

Nephron. 1994;68(1):57-62. doi: 10.1159/000188088.

Effect of pravastatin on outcomes after cardiac transplantation.普伐他汀对心脏移植术后结局的影响。

N Engl J Med. 1995 Sep 7;333(10):621-7. doi: 10.1056/NEJM199509073331003.

[Rhabdomyolysis in patients treated with simvastatin and cyclosporin: role of the hepatic cytochrome P450 enzyme system activity].

Schweiz Med Wochenschr. 1995 Jul 11;125(27-28):1342-6.

Risk factors for accelerated atherosclerosis in renal transplant recipients.肾移植受者加速动脉粥样硬化的危险因素。

Am J Med. 1988 Jun;84(6):985-92. doi: 10.1016/0002-9343(88)90302-6.

Low-dose lovastatin safely lowers cholesterol after cardiac transplantation.小剂量洛伐他汀可安全降低心脏移植后的胆固醇水平。

Circulation. 1990 Nov;82(5 Suppl):IV281-3.

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