药物外排作为一种耐药机制。
Drug efflux as a mechanism of resistance.
作者信息
Williams J B
机构信息
Department of Biology, Birkbeck College, University of London, England, UK.
出版信息
Br J Biomed Sci. 1996 Dec;53(4):290-3.
PMID:9069107
Abstract
A review of efflux as a mechanism of antibiotic resistance in both bacterial and eukaryotic cells is presented. This covers membrane transport, the evolution of efflux transporters, their genetic control and classification into families, and an appreciation of the widespread distribution and occurrence of these mechanisms in nature.
摘要
本文综述了外排作为细菌和真核细胞抗生素耐药机制的相关内容。这涵盖了膜转运、外排转运体的进化、它们的基因调控以及按家族分类，还阐述了这些机制在自然界中的广泛分布和存在情况。
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