Okuno T, Okuno T, Matsuo M, Higa T, Hattori H
Medical Center for Children, Shiga.
No To Hattatsu. 1997 Mar;29(2):123-8.
Recent progress in magnetic resonance imaging (MRI) has successfully visualized neuronal migration disorders (NMDs) without autopsy. NMDs are observed in the patients with hydranencephaly, porencephaly, cerebellar hypoplasia, agenesis of corpus callosum, agenesis of septum pellucidum and holoprocencephaly. Miller-Dieker syndrome, Fukuyama-type congenital muscular dystrophy, Walker-Warburg syndrome, hypomelanosis of Ito, congenital rubella syndrome, toxoplasmosis, Zellweger syndrome and other diseases are also associated with lissencephaly, pachygyria and polymicrogyria. Neuroimagings of illustrative cases with NMDs were shown here.
磁共振成像（MRI）的最新进展已成功实现无需尸检即可可视化神经元迁移障碍（NMDs）。在无脑回畸形、脑穿通畸形、小脑发育不全、胼胝体发育不全、透明隔发育不全和前脑无裂畸形患者中可观察到NMDs。米勒-迪克尔综合征、福山型先天性肌营养不良、沃克-沃尔堡综合征、伊藤色素减退症、先天性风疹综合征、弓形虫病、泽尔韦格综合征及其他疾病也与无脑回、巨脑回和多小脑回畸形有关。此处展示了NMDs典型病例的神经影像学表现。
