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1986 - 1993年马里兰州儿童结核病的病例特征与趋势

Case characteristics and trends in pediatric tuberculosis, Maryland, 1986-1993.

作者信息

Chaulk C P, Khoo L, Matuszak D L, Israel E

机构信息

Annie E. Casey Foundation, Baltimore MD 21202, USA.

出版信息

Public Health Rep. 1997 Mar-Apr;112(2):146-52.

Abstract

OBJECTIVE

To identify case characteristics and trends in the incidence of pediatric tuberculosis (TB) in Maryland during the national resurgence of the disease.

METHODS

The authors conducted a retrospective review of the 248 cases of TB in children ages 19 and younger reported to the state registry between 1986 and 1993.

RESULTS

The incidence of pediatric TB in Maryland, while showing a downward trend between 1986 and 1993, was characterized by a bimodal pattern, with one peak in children younger than age 5 and another peak in adolescents. Certain case characteristics differed significantly according to age: adolescents with TB were more likely to have positive AFB smears, positive cultures, and cavitary X-rays than children in the 0-4 age group. On the other hand, PPD results did not differ significantly by age. Children with TB came from households in zip code areas for which the median family income was lower and the rate of unemployment was higher than comparable statewide figures.

CONCLUSIONS

Study findings indicate that (a) the general decline in adult TB in Maryland was accompanied by a decline among children; (b) age-specific case characteristics continue to be useful in clinical decision making for children with suspected TB; and (c) a state TB registry may prove useful not only in tracking disease trends and monitoring statewide control efforts but also in confirming case characteristics, all of which are important disease control issues in a time of fiscal downsizing.

摘要

目的

确定在全国结核病疫情回升期间,马里兰州儿童结核病(TB)的病例特征及发病率趋势。

方法

作者对1986年至1993年间向该州登记处报告的19岁及以下儿童的248例结核病病例进行了回顾性研究。

结果

马里兰州儿童结核病发病率在1986年至1993年间呈下降趋势,其特征为双峰模式,一个高峰出现在5岁以下儿童中,另一个高峰出现在青少年中。某些病例特征在不同年龄段存在显著差异:结核病青少年比0 - 4岁年龄组的儿童更有可能出现抗酸杆菌涂片阳性、培养阳性及空洞性X光表现。另一方面,结核菌素试验(PPD)结果在不同年龄组间无显著差异。结核病儿童来自家庭收入中位数较低且失业率高于全州可比数据的邮政编码区域的家庭。

结论

研究结果表明:(a)马里兰州成人结核病的总体下降伴随着儿童结核病的下降;(b)特定年龄的病例特征在疑似结核病儿童的临床决策中仍然有用;(c)一个州结核病登记处可能不仅在追踪疾病趋势和监测全州防控工作方面有用,而且在确认病例特征方面也有用,在财政紧缩时期,所有这些都是重要的疾病控制问题。

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