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[急性肠道感染和慢性结肠炎伴腹泻患者的肠吸附治疗]

[The enterosorption treatment of patients with acute intestinal infections and chronic colitis with diarrhea].

作者信息

Andreĭchyn M A, Lutsuk O S, Andreĭchyn S M, Kopcha V S

出版信息

Lik Sprava. 1996 Jul-Sep(7-9):147-51.

PMID:9072235
Abstract

A total of 234 patients with acute intestinal infections (AII) and chronic colitis presenting with diarrhoea were examined. In an acute phase of AII induced by conditionally pathogenic flora, salmonellae and shigellae, as well as in exacerbation of chronic colitis, blood aggregability appears to be on the increase, with the ability of erythrocytes to deformation getting worse. In rectal mucosa hemodynamic disorders are common, manifested by decrease in pulse blood filling, rate of bloodflow predominantly in small and medium-size arteries as well as blood supply as a whole. Applying polysorb to rectal mucosa of such patients with the aid of an atomizer in speedier manner than it is usually done in conventional modes of treatment makes for regression of clinical symptoms of the illness, decreases the level of endotoxicosis, speeds up normalization of blood aggregability, red cell deformability, promoting quick restoration of rectal mucose bloodflow, the anal canal sphincter strength, with its rigidity returning to normal.

摘要

对总共234例患有急性肠道感染(AII)和伴有腹泻的慢性结肠炎患者进行了检查。在由条件致病性菌群、沙门氏菌和志贺氏菌引起的AII急性期以及慢性结肠炎加重期,血液聚集性似乎增加,红细胞变形能力变差。直肠黏膜血流动力学紊乱很常见,表现为脉搏充血减少、主要在中小动脉的血流速度以及整体血液供应减少。与传统治疗方式相比,借助雾化器以更快的速度将聚山梨醇酯应用于这类患者的直肠黏膜,可使疾病的临床症状消退,降低内毒素血症水平,加快血液聚集性、红细胞变形能力的正常化,促进直肠黏膜血流、肛管括约肌强度迅速恢复,使其硬度恢复正常。

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