• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[New chemical method for synthesis of O-linked glycopeptides].

作者信息

Polt R L, Szabo L, Ramza J

机构信息

Department of Chemistry, University of Arizona, Tucson, USA.

出版信息

Postepy Hig Med Dosw. 1996;50(5):493-503.

PMID:9072765
Abstract

The diphenylketone Shiff-base appeared to be a very good protection from amino groups of serine and threonine for glycosylation reaction. O-Glycosides of these amino acids with different monosaccharides, aminosugars and deoxysugars were obtained with excellent yield and very high stereoselectivity. Products of glycosylation reactions were used as building blocks for solid phase glycopeptide synthesis.

摘要

相似文献

1
[New chemical method for synthesis of O-linked glycopeptides].
Postepy Hig Med Dosw. 1996;50(5):493-503.
2
An efficient synthetic route to glycoamino acid building blocks for glycopeptide synthesis.一种用于糖肽合成的糖氨基酸构建块的高效合成路线。
Org Lett. 2004 Oct 28;6(22):4001-4. doi: 10.1021/ol048342n.
3
Conformational consequences of protein glycosylation: preparation of O-mannosyl serine and threonine building blocks, and their incorporation into glycopeptide sequences derived from alpha-dystroglycan.蛋白质糖基化的构象后果:O-甘露糖基丝氨酸和苏氨酸结构单元的制备及其掺入源自α-肌营养不良蛋白聚糖的糖肽序列中。
Biopolymers. 2008;90(3):358-68. doi: 10.1002/bip.20847.
4
A concise methodology for the stereoselective synthesis of O-glycosylated amino acid building blocks: complete 1H NMR assignments and their application in solid-phase glycopeptide synthesis.一种立体选择性合成O-糖基化氨基酸构建单元的简明方法:完整的¹H NMR归属及其在固相糖肽合成中的应用
J Pept Res. 1998 Sep;52(3):165-79. doi: 10.1111/j.1399-3011.1998.tb01473.x.
5
Glycopeptide and glycoprotein synthesis involving unprotected carbohydrate building blocks.涉及未保护碳水化合物构建单元的糖肽和糖蛋白合成。
Med Res Rev. 2005 Nov;25(6):655-78. doi: 10.1002/med.20033.
6
Preparation of glycosylated amino acids suitable for Fmoc solid-phase assembly.适用于Fmoc固相组装的糖基化氨基酸的制备。
Methods Mol Biol. 2008;494:187-208. doi: 10.1007/978-1-59745-419-3_11.
7
Efficient synthesis of complex glycopeptides based on unprotected oligosaccharides.基于未保护寡糖的复杂糖肽的高效合成。
J Org Chem. 2003 Apr 4;68(7):2713-9. doi: 10.1021/jo020570c.
8
Solution-phase synthesis with solid-state workup of an O-glycopeptide with a cluster of cancer-related T antigens.具有一组癌症相关T抗原的O-糖肽的溶液相合成及固相后处理
Org Lett. 2005 Aug 4;7(16):3589-92. doi: 10.1021/ol0514193.
9
Extended sugar-assisted glycopeptide ligations: development, scope, and applications.扩展的糖辅助糖肽连接:发展、范围及应用
J Am Chem Soc. 2007 Nov 7;129(44):13527-36. doi: 10.1021/ja073653p. Epub 2007 Oct 13.
10
Synthesis of N-linked glycopeptides via solid-phase aspartylation.通过固相天冬酰化合成 N-连接糖肽。
Org Biomol Chem. 2010 Aug 21;8(16):3723-33. doi: 10.1039/c003673k. Epub 2010 Jun 21.

引用本文的文献

1
PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia.PNA5,一种新型的 Mas 受体激动剂,可改善血管性认知障碍和痴呆小鼠模型的神经血管和血脑屏障功能。
Aging Dis. 2024 Aug 1;15(4):1927-1951. doi: 10.14336/AD.2023.0928.