Osther P J, Gjøde P, Mortensen B B, Mortensen P B, Andersen J B, Gottrup F
Odense Universitetshospital, kirurgisk afdeling A, København.
Ugeskr Laeger. 1997 Feb 17;159(8):1100-3.
A randomized study of abdominal fascial closure using interrupted polyglyconate and polyglycolic acid sutures after laparotomy was carried out in 204 consecutive patients with suspected impaired wound healing. There were no statistically significant differences between the two sutures with regard to development of fascial disruption and incisional hernia. Wound infection demanding surgical intervention was found in 7% of patients with polyglyconate sutures and in 16% of those with polyglycolic acid sutures (p = 0.04). Monofilament polyglyconate suture does not reduce the incidence of fascial disruption and incisional hernia after laparotomy in patients with suspected impaired wound healing but the incidence of wound infection may be reduced compared with that of multifilament polyglycolic acid suture.
对204例连续的疑似伤口愈合受损患者进行了一项随机研究，比较剖腹术后使用间断聚甘醇酸缝线和聚乙醇酸缝线进行腹部筋膜缝合的效果。在筋膜裂开和切口疝的发生方面，两种缝线之间无统计学显著差异。使用聚甘醇酸缝线的患者中有7%出现需要手术干预的伤口感染，而使用聚乙醇酸缝线的患者中有16%出现此类感染（p = 0.04）。对于疑似伤口愈合受损的患者，单丝聚甘醇酸缝线并不能降低剖腹术后筋膜裂开和切口疝的发生率，但与多丝聚乙醇酸缝线相比，其伤口感染发生率可能会降低。
