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鼻前庭鳞状细胞癌的近距离放射治疗。

Brachytherapy of squamous cell carcinoma of the nasal vestibule.

作者信息

Evensen J F, Jacobsen A B, Tausjø J E

机构信息

Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, Oslo.

出版信息

Acta Oncol. 1996;35 Suppl 8:87-92. doi: 10.3109/02841869609098525.

DOI:10.3109/02841869609098525
PMID:9073053
Abstract

From 1985 to 1994, 23 patients with squamous cell carcinoma of the nasal vestibule were treated by brachytherapy. The TNM stage was as follows: T1N0 (9 patients), T2N0 (11 patients) and T4N0 (3 patients). Four patients had primary surgery and postoperative brachytherapy, whereas 12 patients had brachytherapy alone and 7 had tele- and brachytherapy in combination. For brachytherapy, the plastic tube technique was used. With the exception of one patient with a partial response, complete response was obtained in all patients. Two patients relapsed: one (T4N0) locally after 5 months and one (T2N0) regionally after 12 months. Both are alive and with no evidence of disease after salvage surgery. For early stage carcinoma (T1, T2) of the nasal vestibule, brachytherapy is a safe treatment yielding a high grade of local control and with good cosmetic results.

摘要

1985年至1994年期间,对23例鼻前庭鳞状细胞癌患者进行了近距离放射治疗。TNM分期如下:T1N0(9例)、T2N0(11例)和T4N0(3例)。4例患者接受了原发手术及术后近距离放射治疗,12例患者仅接受近距离放射治疗,7例患者接受了远距离和近距离放射治疗联合治疗。近距离放射治疗采用塑料导管技术。除1例部分缓解患者外,所有患者均获得完全缓解。2例患者复发:1例(T4N0)在5个月后局部复发,1例(T2N0)在12个月后区域复发。经挽救性手术后,两人均存活且无疾病证据。对于鼻前庭早期癌(T1、T2),近距离放射治疗是一种安全的治疗方法,可实现高度的局部控制,且美容效果良好。

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Eur Arch Otorhinolaryngol. 2016 Jun;273(6):1543-7. doi: 10.1007/s00405-015-3636-3. Epub 2015 Apr 24.