Purola E, Vartiainen E
Ann Chir Gynaecol. 1977;66(4):216-8.
Eight postclimacteric women were given 80 mg polyestriol phosphate by intramuscular injection in order to analyse the effect of the drug on the vaginal cytology. In four patients, whose vaginal smears showed complete atrophy before treatment, a clear but weak oestrogen effect was observed after the medication. This effect appeared after one week in three patients and after two weeks in one patient, and it lasted four weeks in three cases and two weeks in one. In four patients, whose vaginal smears showed a weak oestrogen effect before treatment, the therapy did not result in any significant change of the vaginal smear pattern.
八名绝经后女性接受了80毫克磷酸聚雌三醇的肌肉注射，以分析该药物对阴道细胞学的影响。在四名治疗前阴道涂片显示完全萎缩的患者中，用药后观察到明显但微弱的雌激素效应。三名患者在用药一周后出现这种效应，一名患者在两周后出现，三名患者这种效应持续四周，一名患者持续两周。在四名治疗前阴道涂片显示微弱雌激素效应的患者中，治疗未导致阴道涂片模式发生任何显著变化。
