Moriyama K, Okamura T, Nakano S
Immunology Division, Jichi Medical School, Tochigi-Ken, Japan.
Br J Haematol. 1997 Mar;96(4):864-7. doi: 10.1046/j.1365-2141.1997.d01-2105.x.
GB virus C (GBV-C) RNA was detected in five of 18 patients with aplastic anaemia who had received blood transfusions, whereas it was not detected in eight patients who had not received any transfusions. Antibody against hepatitis C virus (anti-HCV) was detected in nine patients in the transfusion group, compared with one of eight who had not received any transfusions. Therefore, the route of transmission of both GBV-C and HCV in these patients appeared to have been multiple blood transfusion. Since all of the GBV-C RNA-positive patients harboured anti-HCV, GBV-C seems to frequently superinfect with HCV. Neither GBV-C nor HCV is likely to have been a causative agent of the anaemia in the cases examined.
在18例接受输血的再生障碍性贫血患者中，有5例检测到GB病毒C型（GBV-C）RNA，而在8例未接受任何输血的患者中未检测到。输血组中有9例患者检测到丙型肝炎病毒抗体（抗-HCV），而未接受任何输血的8例患者中有1例检测到。因此，这些患者中GBV-C和HCV的传播途径似乎都是多次输血。由于所有GBV-C RNA阳性患者都携带抗-HCV，GBV-C似乎经常与HCV发生重叠感染。在所检查的病例中，GBV-C和HCV都不太可能是贫血的病因。
