Anderson D E, Midla L T, Scrivani P V, Rosario J, Léveillé R, Long J F, Hull B L
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210, USA.
J Am Vet Med Assoc. 1997 Mar 15;210(6):808-10.
A 3.3-year-old 125-kg castrated male llama was evaluated because of acute non-weight-bearing lameness on the left hind limb. Physical examination revealed crepitus in the midportion of the femur. On radiographs, a comminuted middiaphyseal fracture was seen. There was also a region of bone lysis with cortical thinning and expansion in the distal metaphysis and epiphysis of the left femur. Multiple small circular lesions were observed in the proximal metaphysis of the left femur, and the proximal portion of the left tibia appeared irregular. The owner elected to pursue treatment, and the fracture was repaired with 2 compression plates. Multiple bone biopsy specimens were obtained and submitted for bacterial culture and histologic examination. Cultures yielded neither bacteria nor fungi. Histologic examination revealed fibrous connective tissue, normal appearing cortical bone, and an absence of medullary structures. The llama was maintained in a hind-limb sling for 14 days after surgery, at which time follow-up radiography revealed a comminuted fracture of the proximal portion of the femur. The llama was euthanatized, and multifocal polyostotic aneurysmal bone cysts were found in the proximal and distal metaphyses of the left femur and tibia. Cysts were lined by fibroblasts or endothelial-like cells.
一只3.3岁、体重125千克的去势雄性美洲驼因左后肢急性非负重性跛行前来就诊。体格检查发现股骨中部有摩擦音。X线片显示股骨干中段粉碎性骨折。左股骨远端干骺端和骨骺处还有骨质溶解区域，伴有皮质变薄和骨质膨胀。在左股骨近端干骺端观察到多个小圆形病灶，左胫骨近端看起来不规则。主人决定进行治疗，骨折用2块加压钢板修复。获取了多个骨活检标本并送去进行细菌培养和组织学检查。培养结果未发现细菌和真菌。组织学检查显示为纤维结缔组织、外观正常的皮质骨以及髓质结构缺失。术后这只美洲驼在后肢吊带中固定了14天，此时随访X线片显示股骨近端粉碎性骨折。这只美洲驼实施了安乐死，在左股骨和胫骨的近端和远端干骺端发现了多灶性多囊性骨囊肿。囊肿内衬有成纤维细胞或内皮样细胞。
