Loder R T, Hensinger R N
Section of Orthopaedic Surgery, School of Medicine, University of Michigan, Ann Arbor, USA.
J Pediatr Orthop. 1997 Mar-Apr;17(2):205-11. doi: 10.1097/00004694-199703000-00013.
A retrospective institutional and literature review of 31 children (20 boys and 11 girls) with 58 renal failure-associated slipped capital femoral epiphyses (RFASCFEs) was performed. The average age at diagnosis of renal failure was 8.9 years, and for RFASCFE 11.5 years, with a linear correlation between these two ages. All patients had secondary hyperparathyroidism at diagnosis of the RFASCFE. The median height and weight were below the 5th percentile. The RFASCFEs were stable and bilateral in 95% of the children. Slip magnitude was mild in 53%, moderate in 8%, and severe in 39%. Avascular necrosis was associated with steroid immunosuppression in children with renal transplants. All children were treated with medical management; surgery was used in an additional 29 hips. If correction of secondary hyperparathyroidism is not achieved within 2 months, RFASCFEs are likely to progress and surgical stabilization is recommended.
对31例患有58例肾衰竭相关的股骨头骨骺滑脱（RFASCFE）的儿童（20名男孩和11名女孩）进行了一项回顾性的机构和文献研究。肾衰竭诊断时的平均年龄为8.9岁，RFASCFE诊断时的平均年龄为11.5岁，这两个年龄之间存在线性相关性。所有患者在RFASCFE诊断时均患有继发性甲状旁腺功能亢进。中位身高和体重低于第5百分位数。95%的儿童RFASCFE稳定且为双侧性。53%的滑脱程度为轻度，8%为中度，39%为重度。肾移植儿童的缺血性坏死与类固醇免疫抑制有关。所有儿童均接受药物治疗；另外29个髋关节采用了手术治疗。如果在2个月内未实现继发性甲状旁腺功能亢进的纠正，RFASCFE可能会进展，建议进行手术固定。
