Il'in G I, Parusiv V N
Arkh Patol. 1977;39(7):3-14.
The analysis of most important publications and the authors' own data on the pathological anatomy and pathogenesis of influenza are presented. Severe complicated forms of influenza are characterized by the development of acute bacterial tracheobronchites which are the source of staphylococcal aspirations into the lungs. The degree of severity of developing pneumonias is determined to a large extent by destructive changes in the lungs. The destruction of osmiophilic bodies in the alveolar epithelium and the disturbance of the surfactant system is conducive to pulmonary edema. An important role in the involvement of the lungs and other organs is played by viralstaphylococcal toxicity. Lymphoid-macrophage and leukocyte reactions responsible for the production of antibody, interferon, and other factors of resistance are very important for protection against influenza. During epidemics, particular attention should be paid to combinations of influenza with cardio-vascular diseases.
本文对关于流感病理解剖学和发病机制的最重要出版物以及作者自己的数据进行了分析。重症流感复杂形式的特征是急性细菌性气管支气管炎的发展，这是葡萄球菌吸入肺部的来源。所发生肺炎的严重程度在很大程度上取决于肺部的破坏性变化。肺泡上皮中嗜锇性小体的破坏以及表面活性剂系统的紊乱会导致肺水肿。病毒 - 葡萄球菌毒性在肺部和其他器官受累中起重要作用。负责产生抗体、干扰素和其他抵抗因子的淋巴 - 巨噬细胞和白细胞反应对于预防流感非常重要。在流感流行期间，应特别关注流感与心血管疾病的合并情况。
