肺炎链球菌产生一种不同于肺炎溶血素的第二种溶血素。

Streptococcus pneumoniae produces a second haemolysin that is distinct from pneumolysin.

作者信息

Canvin J R, Paton J C, Boulnois G J, Andrew P W, Mitchell T J

机构信息

Department of Microbiology and Immunology, University of Leicester, U.K.

出版信息

Microb Pathog. 1997 Mar;22(3):129-32. doi: 10.1006/mpat.1996.0098.

DOI:10.1006/mpat.1996.0098

PMID:9075215

Abstract

Pneumococci are described as alpha-haemolytic but under certain circumstances they produce zones of beta-haemolysis on blood-containing medium. This observation was investigated using wild type strains and a genetically-modified strain unable to produce the haemolytic toxin, pneumolysin. beta-haemolysis was produced by all pneumococci tested. It was not inhibited by anti-pneumolysin antibody but could be inactivated by cholesterol. These data confirm that pneumococci elaborate a second haemolysin, distinct from pneumolysin.

摘要

肺炎球菌被描述为α溶血，但在某些情况下，它们在含血培养基上会产生β溶血区域。使用野生型菌株和一种无法产生溶血毒素肺炎溶血素的基因改造菌株对这一观察结果进行了研究。所有测试的肺炎球菌都产生了β溶血。它不受抗肺炎溶血素抗体的抑制，但可被胆固醇灭活。这些数据证实肺炎球菌会产生第二种溶血素，与肺炎溶血素不同。