Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z, Barlas O
Department of Neurosurgery, Istanbul University School of Medicine, Turkey.
Pediatr Neurosurg. 1996 Aug;25(2):94-9. doi: 10.1159/000121103.
Gliomatosis cerebri is an infrequent tumor of neuroepithelial origin presenting with deterioration of cognitive functions, behavioral and mental changes, motor weakness, headache, and seizures. Laboratory data are unconclusive. MRI appears to be the imaging modality of choice and mainly reveals a bilateral and diffuse infiltration of midline adjacent brain structures whose anatomical configuration remain intact. MRI- or CT-guided stereotactic biopsy is advised as the diagnostic procedure in suspected cases. A 9-year-old girl with diffuse cerebrospinal gliomatosis, investigated with sequential cranial CT scans, and MRI-verified spinal cord involvement is reported, and the corresponding literature is reviewed.
大脑胶质瘤病是一种罕见的神经上皮源性肿瘤，表现为认知功能减退、行为和精神改变、运动无力、头痛和癫痫发作。实验室检查结果尚无定论。MRI似乎是首选的影像学检查方法，主要显示中线相邻脑结构的双侧弥漫性浸润，其解剖结构保持完整。对于疑似病例，建议采用MRI或CT引导下的立体定向活检作为诊断方法。本文报告了一名9岁弥漫性脑脊膜胶质瘤病女孩，通过连续头颅CT扫描进行检查，并经MRI证实脊髓受累，同时对相关文献进行了综述。
