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胃癌患者的红细胞脂质过氧化与抗氧化剂

Erythrocyte lipid peroxidation and antioxidants in gastric cancer patients.

作者信息

Arivazhagan S, Kavitha K, Nagini S

机构信息

Department of Biochemistry, Faculty of Science, Annamalai University, Tamil Nadu, India.

出版信息

Cell Biochem Funct. 1997 Mar;15(1):15-8. doi: 10.1002/(SICI)1099-0844(199703)15:1<15::AID-CBF704>3.0.CO;2-3.

Abstract

The present study has analysed the relationship between lipid peroxidation and antioxidant status in erythrocytes from 24 adult male gastric cancer patients and an equal number of age- and sex-matched normal subjects. Erythrocyte lipid peroxidation was markedly increased. Both enzymic and non-enzymic antioxidants were decreased in erythrocytes of gastric cancer patients. The present study highlights the occurrence of lipid peroxidation and possible breakdown of antioxidant status in patients with gastric carcinoma.

摘要

本研究分析了24名成年男性胃癌患者及同等数量年龄和性别匹配的正常受试者红细胞中脂质过氧化与抗氧化状态之间的关系。结果显示,胃癌患者红细胞中的脂质过氧化显著增加,同时酶促抗氧化剂和非酶促抗氧化剂均减少。本研究突出了胃癌患者中脂质过氧化的发生以及抗氧化状态可能的破坏。

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