Barker S L, Shortreed M R, Kopelman R
Department of Chemistry, University of Michigan, Ann Arbor 48109-1055, USA.
Anal Chem. 1997 Mar 15;69(6):990-5. doi: 10.1021/ac960700f.
Lipophilic anionic and cationic additives are investigated as components for use in liquid polymer film-based optodes. These ionic additives are known to strongly influence the selectivity behavior of anion-selective electrodes. They also make it possible to construct ion coextraction optodes that can measure anion activities. Theoretical, thermodynamic anion-optode equilibria formalisms were derived to help understand the influence these additives have on the overall optode response and on the selectivity behavior. Neutral and charged anion carrier film configurations are described and tested for two anion ionophores with known modes of action, ruthenium(II) octaethylporphyrin and a vitamin B12 derivative (cyanoaquacobyrinic acid heptakis(2-phenylethyl ester)). These film configurations were further tested using a less well-understood ionophore, indium(III) octaethylporphyrin. Notable is the indium(III) octaethylporphyrin optode, which has a dynamic range appropriate for physiological measurements of chloride at neutral pH values. Also of interest is the optode with the vitamin B12 derivative ionophore, which has a dynamic range appropriate for some physiological measurements of nitrite at neutral pH values.
研究了亲脂性阴离子和阳离子添加剂作为基于液体聚合物膜的光极组件的应用。已知这些离子添加剂会强烈影响阴离子选择性电极的选择性行为。它们还使得构建能够测量阴离子活性的离子共萃取光极成为可能。推导了理论热力学阴离子光极平衡形式，以帮助理解这些添加剂对整体光极响应和选择性行为的影响。描述并测试了中性和带电阴离子载体膜配置，用于两种已知作用模式的阴离子载体，钌（II）八乙基卟啉和维生素B12衍生物（氰基水合钴胺酸庚基（2-苯乙酯））。使用一种了解较少的载体铟（III）八乙基卟啉进一步测试了这些膜配置。值得注意的是铟（III）八乙基卟啉光极，其动态范围适合在中性pH值下对氯离子进行生理测量。同样有趣的是含有维生素B12衍生物载体的光极，其动态范围适合在中性pH值下对亚硝酸盐进行一些生理测量。
