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噻氯匹定在经皮腔内冠状动脉成形术(PTCA)后预防血栓形成中的应用。

Ticlopidine in the prevention of thrombus formation after percutaneous transluminal coronary angioplasty (PTCA).

作者信息

Chotinaiwattarakul C, Mahanonda N, Kangkagate C, Chaithiraphan S

机构信息

Her Majesty's Cardiac Centre, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 1997 Feb;80(2):76-80.

PMID:9078690
Abstract

We studied the additive effect of ticlopidine to aspirin compared with aspirin in the prevention of thrombus formation after PTCA in two groups of 21 patients who underwent PTCA at Her Majesty's Cardiac Centre, Siriraj Hospital from January to April 1993. Patients in both groups were comparable in baseline patient data and characteristics of angiographic lesions. There was no difference in angiographic outcome including the presence of intracoronary thrombus between the two groups. We concluded that ticlopidine had no additive effect to aspirin in the prevention of thrombus formation after PTCA.

摘要

1993年1月至4月期间,我们在诗里拉吉医院女王心脏中心对两组各21例接受经皮冠状动脉腔内血管成形术(PTCA)的患者进行了研究,比较噻氯匹定与阿司匹林联合使用及单独使用阿司匹林在预防PTCA术后血栓形成方面的附加效果。两组患者的基线数据和血管造影病变特征具有可比性。两组在血管造影结果方面,包括冠状动脉内血栓的存在情况,均无差异。我们得出结论,在预防PTCA术后血栓形成方面,噻氯匹定对阿司匹林没有附加效果。

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