Carbon dioxide output and elimination in children under anaesthesia.

The requirements for fresh gas inflow with the Bain breathing circuit in children was examined by determining the PaCO2 in 46 children during controlled ventilation with a total fresh gas inflow of 3.5 l/min and by measuring the carbon dioxide output in 83 children under anaesthesia. It could be shown that all children below 40 kg body weight had a PaCO2 below 40 torr (5.32 kPa) and the PaCO2 paralleled the body weight, i.e., the lowest carbon dioxide tension was seen in children under 10 kg. As expected, the highest carbon dioxide output was found in children below 5 kg body weight; the carbon dioxide output per kilogram decreased with increasing body weight up to 30-35 kg and remained at that level in larger children. Children in their teens, although they may have attained adult body weight, had a higher carbon dioxide output than adults. Based on these findings, our recommendation of a total fresh gas inflow of 3.5 1/min for all children would appear adequate for a body weight up to 35 kg on controlled ventilation. In children under 10 kg body weight, a reduction of the total fresh gas flow to two litres per minute will avoid marked respiratory alkalosis. For children over 35 kg, a fresh gas flow of 100 ml/kg/min should be satisfactory during controlled ventilation.