Misselevich I, Podoshin L, Fradis M, Boss J H
Department of Pathology, Bnai-Zion Medical Center, Haifa, Israel.
Ann Otol Rhinol Laryngol. 1997 Mar;106(3):226-9. doi: 10.1177/000348949710600308.
A 44-year-old woman underwent a partial parotidectomy for a slowly enlarging parotid mass diagnosed by fine needle aspiration biopsy as a pleomorphic adenoma. Though macroscopically recognized to be composed of two nodules, differing to some extent from one another, the mass appeared to constitute a single tumor. The microscopic examination disclosed two disparate neoplasms, which were separated from each other by a thin fibrous band. The larger of the two nodules was a pleomorphic adenoma and the smaller one an acinic cell carcinoma. The metachronous--and, even more, the synchronous--occurrence of two histologically different tumors in one major salivary gland is an exceptional and probably coincidental event.
一名44岁女性因腮腺肿块逐渐增大接受了腮腺部分切除术。该肿块经细针穿刺活检诊断为多形性腺瘤。尽管肉眼可见肿块由两个结节组成,二者在一定程度上有所不同,但似乎构成一个单一肿瘤。显微镜检查发现两个不同的肿瘤,它们被一条薄纤维带分隔开。两个结节中较大的一个是多形性腺瘤,较小的一个是腺泡细胞癌。在一个主要唾液腺中同时出现——甚至更是异时出现——两种组织学不同的肿瘤是一种罕见且可能是巧合的事件。