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抗精神病药物:文献综述及其对精神卫生护理的启示

Neuroleptic medication: the literature and implications for mental health nursing.

作者信息

Usher K, Happell B

机构信息

Department of Nursing Sciences, James Cook University, Townsville, Qld, Australia.

出版信息

Aust N Z J Ment Health Nurs. 1996 Dec;5(4):191-8.

PMID:9079316
Abstract

The past twenty years have been a period of consolidation in the pharmacotherapy of schizophrenia followed more recently by a period where a number of new, atypical neuroleptics have enhanced the treatment options available to people with schizophrenia. In this article the contemporary research into neuroleptic medications, the mainstay of treatment for schizophrenia, is reviewed and critiqued. In particular, the article addresses important issues such as drug efficacy and action, the therapeutic effects of neuroleptics, side effects, including the recent research related to these side effects and, finally, the implications for mental health nurses. The issues raised here have sufficient relevance for mental health nurses for items to be considered in all undergraduate nursing and postgraduate mental health nursing courses.

摘要

在过去的二十年里,精神分裂症药物治疗处于巩固阶段,最近又出现了一些新型非典型抗精神病药物,增加了精神分裂症患者的治疗选择。本文对作为精神分裂症主要治疗手段的抗精神病药物的当代研究进行了综述和批判。特别是,本文讨论了一些重要问题,如药物疗效与作用、抗精神病药物的治疗效果、副作用,包括与这些副作用相关的最新研究,以及对精神科护士的影响。这里提出的问题与精神科护士密切相关,所有本科护理课程和研究生精神科护理课程都应予以考虑。

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