Pfanner N, Meijer M
Institut für Biochemie und Molekularbiologie, Universität Freiburg, Freiburg, Germany.
Curr Biol. 1997 Feb 1;7(2):R100-3. doi: 10.1016/s0960-9822(06)00048-0.
Translocation of precursor proteins into mitochondria depends on loosely assembled protein complexes in the outer and inner membranes. Recent studies indicate that dynamic interactions of subcomplexes and cooperation with molecular chaperones drive key steps in protein import.
前体蛋白转运至线粒体取决于外膜和内膜中松散组装的蛋白复合物。最近的研究表明,亚复合物的动态相互作用以及与分子伴侣的协同作用推动了蛋白质导入过程中的关键步骤。