Buc H
Biologie Moleculaire, Institut Pasteur, Paris, France.
Curr Biol. 1997 Feb 1;7(2):R97-9. doi: 10.1016/s0960-9822(06)00047-9.
Recent findings help to define the multiple functions of the sigma subunit of bacterial RNA polymerase, from promoter recognition to the release of pausing during initial RNA elongation; these functions can now be confronted with a crystal structure of an essential domain of the sigma subunit.
最近的研究结果有助于明确细菌RNA聚合酶σ亚基的多种功能,从启动子识别到初始RNA延伸过程中暂停的解除;现在可以将这些功能与σ亚基一个关键结构域的晶体结构进行对照研究。