Ulrich S, Kalder M, Hitschold T, Weiss E, Berle P
Frauenklinik der Dr.-Horst-Schmidt-Kliniken, Wiesbaden.
Zentralbl Gynakol. 1996;118(11):605-9.
We analysed 78 fetuses with absent or reverse endiastolic flow velocities (AREDFV) of the umbilical arteries with respect to fetal acidosis, resistance index of the middle cerebral artery (MCA) and abnormal neurological evaluations. A control group was matched for gestational age and normal umbilical artery flow velocity waveforms. Fetuses with AREDFV showed an increased incidence of fetal acidosis. The number of fetuses with abnormal neurological signs was significantly increased compared to the control group. Most of these fetuses (86%) showed abnormal blood flow velocity waveforms of the middle cerebral arteries called "brain-sparing effect". The combination of premature delivery in the 30th week of gestation, severe idiopathic respiratory distress syndrome, and a resistance index under the 10th percentile in the middle cerebral arteries seems to be a risk factor of the early neurological morbidity in fetus with AREDFV.
我们分析了78例脐动脉舒张末期血流速度缺失或反向（AREDFV）的胎儿，涉及胎儿酸中毒、大脑中动脉（MCA）阻力指数及异常神经学评估。对照组在胎龄和正常脐动脉血流速度波形方面进行了匹配。AREDFV胎儿的胎儿酸中毒发生率增加。与对照组相比，有异常神经学体征的胎儿数量显著增加。这些胎儿中的大多数（86%）表现出大脑中动脉血流速度波形异常，即所谓的“脑保护效应”。妊娠30周早产、严重特发性呼吸窘迫综合征以及大脑中动脉阻力指数低于第10百分位数的组合似乎是AREDFV胎儿早期神经疾病的一个危险因素。
