氟烷麻醉后人血清黄嘌呤氧化酶活性升高。
Elevation of serum xanthine oxidase activity following halothane anesthesia in man.
作者信息
Giler S, Eshel Y, Pinkhas J, Ventura E, Levy E, Urca I, Sperling O, de Vries A
出版信息
Experientia. 1977 Oct 15;33(10):1356-8. doi: 10.1007/BF01920178.
PMID:908414
Abstract
Halothane, but not methoxyflurane, was found to cause specific hepatocellular damage, the hepatotoxicity being prompt but transient. The hepatotoxicity was demonstrated by the elevation in the serum activity of xanthine oxidase, a highly sensitive marker for acute liver damage.
摘要
发现氟烷会引起特定的肝细胞损伤，而甲氧氟烷则不会，这种肝毒性迅速但短暂。黄嘌呤氧化酶的血清活性升高证明了这种肝毒性，黄嘌呤氧化酶是急性肝损伤的一种高度敏感标志物。
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