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[朗杜-奥斯勒病的神经外科方面。关于6例近期病例及文献复习]

[Neurosurgical aspects of Rendu-Osler disease. Apropos of 6 recent cases and review of the literature].

作者信息

Emery E, Redondo A, Ouahes O, Berthelot J L, Bouali I, Rey A

机构信息

Service de Neurochirurgie, Hôpital Beaujon, Clichy.

出版信息

Neurochirurgie. 1996;42(4-5):221-8.

PMID:9084750
Abstract

Six patients with neurological complications in Rendu-Osler-Weber disease were reviewed. There were 4 patients (3 int the same family) with a brain abscess, one patient with a brain abscess and a spinal cord subarachnoid hemorrhage, one patient with a recurrent intracerebral hemorrhage due to a vascular malformation. The infectious complications are related to the presence of pulmonary arterio-venous fistula, which should be treated, whenever diagnosed. Because of the potentially severe outcome of these neurological complications of the Rendu-Osler-Weber disease, screening of the patient's relatives is highly recommended.

摘要

对6例患有遗传性出血性毛细血管扩张症(Rendu-Osler-Weber病)并伴有神经并发症的患者进行了回顾性研究。其中4例(3例来自同一家族)患有脑脓肿,1例患有脑脓肿和脊髓蛛网膜下腔出血,1例因血管畸形出现复发性脑出血。感染性并发症与肺动静脉瘘的存在有关,一旦确诊就应进行治疗。鉴于遗传性出血性毛细血管扩张症这些神经并发症可能产生的严重后果,强烈建议对患者亲属进行筛查。

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