围绕鳞状细胞癌的小汗腺汗管纤维腺瘤：一例报告

Eccrine syringofibroadenoma surrounding a squamous cell carcinoma: a case report.

作者信息

Lele S M, Gloster E S, Heilman E R, Chen P C, Chen C K, Anzil A P, Pozner J N, Reardon M J

机构信息

Department of Pathology, State University of New York Health Science Center at Brooklyn 11203, USA.

出版信息

J Cutan Pathol. 1997 Mar;24(3):193-6. doi: 10.1111/j.1600-0560.1997.tb01576.x.

DOI:10.1111/j.1600-0560.1997.tb01576.x

PMID:9085157

Abstract

A 91-year-old man presented with a 9.0 x 7.0 cm exophytic mass on the dorsum of the right foot, surrounded by a scaling hyperkeratotic plaque-like lesion that had been present for many years. He had similar long-standing hyperkeratotic plaque-like lesions on both legs. Histopathologic examination of the exophytic mass revealed a well-differentiated squamous cell carcinoma surrounded by an eccrine syringofibroadenoma (ESFA). Histochemistry, immunohistochemistry and electron microscopy support this diagnosis. To our knowledge, this is the only reported case of ESFA being intimately associated with a malignant neoplasm.

摘要

一名91岁男性患者，右足背出现一个9.0×7.0 cm的外生性肿物，肿物周围有一个已存在多年的鳞屑性角化过度斑块样病变。他的双腿也有类似的长期存在的角化过度斑块样病变。对该外生性肿物进行组织病理学检查，结果显示为高分化鳞状细胞癌，周围伴有小汗腺汗管纤维腺瘤（ESFA）。组织化学、免疫组织化学及电子显微镜检查均支持这一诊断。据我们所知，这是唯一一例报道的ESFA与恶性肿瘤密切相关的病例。